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heart disease symptoms and treatment
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Wilson's disease: Symptoms and Treatment
Wilson's disease is a genetic disease which is fatal unless detected and treated quickly. Is a rare disease in which excess copper accumulates in the body causing copper poisoning. The disease Wilson is rare, affecting 1 to 30,000 people. It is named after Dr. Samuel Wilson, who first described the disorder in 1912.
Copper is a "trace metals" found in many foods. A certain amount of copper intake is necessarily required to stay healthy. Normally, the body automatically eliminates excess copper, but a person suffering from Wilson's disease can not excrete, of course, excessive copper. The result of the gradual decay of excess copper in vital organs like the liver, brain, cornea and kidneys – and it is not treated early, can become life threatening.
In general, the first body part to be affected copper deposits is the liver. In about half of patients with Wilson's disease, the liver is the only organ affected. Excess copper in the hepatocyte cell liver () is harmful and causes liver damage.
Too much copper also impairs brain tissue in an area called the lenticular nucleus. Therefore, Wilson's disease is also called hepato-lenticular degeneration. "If left untreated, damage may be serious and possibly fatal.
What is the cause of Wilson's disease?
The underlying deficit of base in Wilson's disease is unknown. It may be related to body's inability to produce sufficient levels of ceruloplasmin, an enzyme in the liquid part of blood that binds to copper and it is in transport and regulation. Other scientists believe that the reduced production of ceruloplasmin may be the result a defect in the liver's ability to break the copper. The correlation between the decrease in ceruloplasmin and excessive accumulation of copper is not fully understood. In addition, there is also evidence of copper excretion with impaired biliary system.
How works contracting a disease Wilson?
Wilson's disease is a very rare disease. It is mainly genetically linked, consequently, the Most people inherit from their parents. It is also possible that the mutation occurs spontaneously. One in 40,000 people inherit the disease from their Wilson parents, and 1 / 120, 000 (one in four patients with Wilson's disease), to catch the disease from a spontaneous mutation.
What are problems associated with Wilson's disease?
Although the genetic defect is present from birth, it is years for the excess copper to accumulate to toxic levels in which it is fatally damaging.
Symptoms of the disease start usually develop between ages 6 and 20, most often in adolescence. However, it also may develop symptoms adulthood.
The most characteristic sign this disease is the Kayser-Fleischer ring – a rusty brown ring around the cornea of the eye can be seen as an eye exam. Other symptoms, depending on whether the damage occurs in the liver, blood, central nervous system, urinary system, or system musculo-skeletal.
1. Liver problems —
Symptoms of liver problems are often the first to develop. The toxic effect on liver cells can cause hepatitis (liver inflammation), leading to jaundice, abdominal pain and vomiting. If it untreated, damage to liver cells can lead to liver scarring (cirrhosis). Finally, liver cirrhosis and liver failure develop in untreated cases causing severe problems.
2. Brain problems —
That deposits copper in the brain, can cause various symptoms:
• Physical symptoms such as a few tremors in the arms, slowness movements, difficulty with speech (dysphagia), writing problems, difficulty swallowing, a hesitant step, headache, convulsions.
• The psychological symptoms such as depression, mood swings, bizarre behavior and inappropriate depression accompanied by suicidal thoughts, neurosis or psychosis, inability to concentrate. People can become very aggressive and sentimental and can present a "personality change".
If Wilson's disease is not treated, the accumulation of copper in the brain can cause serious problems such as severe muscle weakness, stiffness in the body, and dementia.
3. Other problems –
Copper accumulates in the cornea of the eye. This causes a characteristic called ring Kayser-Fleischer – brown pigmentation of the cornea. Other features may develop anemia, kidney damage, heart problems, pancreatitis (inflammation of pancreas) menstrual problems and repeated miscarriage in women and premature osteoporosis (thinning bones).
Wilson disease is diagnosed by tests that measure the amount of copper in blood, urine and liver.
How is it diagnosed Wilson's Disease?
If Wilson's disease is suspected, a diagnostic tests such as: —
• A blood test to measure ceruloplasmin – A protein that binds copper in the blood.
• A urine test to measure the amount of copper in the urine.
• A review of the cornea may show rings Kayser-Fleischer, whether they were acquired.
• Liver biopsy
If Wilson's disease was confirmed in a person, then brothers and sisters should also be tested to see if they have the condition. Brothers and sisters of person with Wilson's disease is a 1 / 4 Odds having the disease.
Is there a cure for Wilson's disease?
Cure for Disease Wilson requires a liver transplant, which is performed if necessary to save the life of the person. The person still has the genetic defect and the initial damage nervous system will not leave, but can improve.
How Wilson's disease treated?
The goal of drug therapy People with Wilson's disease is to remove excess copper from the body and prevent the continued accumulation of copper deposit. Therefore, treatment should continue throughout life. The sooner the treatment, the better the chances of preventing long-term permanent damage to the liver or brain.
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Stomach problems? Help please?
I was diagnosed with gastric ulcer before 5-6 years, had pain in abdomen and chest, I see a doctor and I feel better after treatment. Now there are about 3 weeks, again, I have a problem with my belly, I digestion, with same symptoms, pain in the left side, all around the heart, at some point in the left arm pain, neck pain and pain in the left back. but with more to think about how I'm going to sleep and I dream, my heart beats immediately and continue increase until the dream I have, as I go hard, then after a while and gradually slow the heart beat to normal. Such is also symptomatic ulcer or any other heart disease or breathing. I also diverted because of nasal symptoms, there three! Help please!
You should see a doctor, not one in Yahoo. And you have answered your question. This could be the heart as well as gastric ulcer. See A. Doctor. If you have pain now, go to the local emergency room now.