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coronary heart disease genetics
Heart Disease Link identified genetic
Scientists have identified a genetic defect that increases the risk of heart disease and heart attacks. Researchers at the U.S. and Canada found that up to four people wearing the white section of DNA that increases the risk of heart disease by 40%. While in Iceland, the researchers found the same genetic variant was linked to a fifth of all heart attacks.
Both research teams directly scanned the genomes of patients with coronary artery disease or had suffered a heart attack to see if there are differences between them and the Healthy People. The United States / Canadian scientists have discovered a section of DNA, called allele, na specific chromosome associated with heart disease. The researchers studied 23,000 people and found those with a copy of this allele have a moderately increased risk of heart disease, while those with two copies, which represents approximately 20-25% of whites are 30 to 40% increased risk of disease heart that the people who have no copies.
Professor Ruth McPherson, University of Ottawa Heart Institute, who worked on the study, said: "The effect is less than that of smoking or having high cholesterol. However, the screening of people in good health for this genetic marker could provide information on future risk of heart disease and help identify individuals who would benefit most early applications of strategies to reduce the risk of heart disease. "
The United States / Canada plan now to see whether the results apply equally to people from black and minority ethnic Asian.
Meanwhile, Iceland, study 17,000 people covered the same DNA strand. They also found that over 20% of people had two copies of the defective allele has led to 60% higher risk of heart attack compared to those with no copies. Dr. Kari Stefansson, who led the research company Decode Genetics, said that if the people at risk of heart attacks were identified, then they may receive medications such as statins, or procedures heart – as well as tips for healthy life – to reduce your risk.
Although the investigation of two groups of scientists who do not know yet why this particular region of the genome is linked to heart disease, although researchers believe it may be associated with hardening and narrowing of the arteries.
Professor Peter Weissberg, medical director of the British Heart Foundation, said: "Trying to find genes that put some families at greater risk of attacks heart is like trying to find a collection of needles scattered amongst a field full of haystacks. The importance of these two studies is that two independent research teams have focused on the same pile of hay. This makes it very likely that approach to the identification of a needle – an important gene in this region. This will be a lot more research and – once found – the gene will be only one of several that are important. This research represents an important step along a very long journey, but a step in the right direction. "
About the Author
Chunterer explores the issue of heart disease including its causes and treatments. It also offers advice on how to avoid heart disease and other related condition. For more information please visit Heart Disease on Chunterer
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Help with biology question!?
Can someone please explain the effect of these factors on coronary heart disease? Sex Age genetic Raza
Genetics has to do with traits that are transmitted. So if a parent has a disease of the offspring may have this function. The older the lowest that the heart receives. It makes sense because the heart works day and night and when your in your 80's is old. Not so sure about sex, but women are more stressed than men. Race does not really matter much.